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한국식품과학회지
→ 한국식품과학회지2017 ; 49(06): 710-713
Anti-inflammatory and anti-atopic effects of corn silk (Zea mays L.) ethanol extracts
옥수수수염 알코올 추출물의 항염 및 항아토피 효과
Hyun Young Kim, Mi-Ja Lee, Woo Duck Seo, Sik-Won Choi, Sun Lim Kim1, Gun-Ho Jung1, and Hyeon Jung Kang*
Crop Foundation Division, National Institute of Crop Science, Rural Development Administration 1Department of Central Area Crop Science, National Institute of Crop Science, Rural Development Administration
김현영·이미자·서우덕·최식원·김선림1·정건호1·강현중*
농촌진흥청 국립식량과학원 작물기초기반과, 1농촌진흥청 국립식량과학원 중부작물부
ABSTRACT
This study evaluates the ability of corn silk (Zea mays L.) extract to function as a natural anti-inflammatory and anti-atopic therapeutic agent. The anti-inflammatory effects of corn silk were evaluated by measuring the inhibitory activities of nitric oxide (NO) and production of tumor necrosis factor-α (TNF-α). Anti-atopic effects were assessed by measuring the repression of thymus and activation-regulated chemokine (TARC). These results indicated that NICS-1 (corn silk ethanol extract) and NICS-3 (high maysin corn silk ethanol extract) functioned as anti-inflammatory agents by down-regulating LPS-induced NO and TNF-α. Additionally, two extracts showed weak repression of TARC expression levels in tumor necrosis factor TNF-α plus IFN-γ induced HaCaT cells, respectively. These results suggest that corn silk extracts have anti-inflammatory and anti-atopic activities, and thus have the potential to reduce and alleviate the symptoms associated with atopic dermatitis.
KEYWORD
corn silk, anti-inflammatory, anti-atopic
한국식품과학회지 2017 Dec; 49(06): 710 - 713
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