→ 한국식품과학회지2017 ; 49(06): 710-713
Anti-inflammatory and anti-atopic effects of corn silk (Zea mays L.) ethanol extracts
옥수수수염 알코올 추출물의 항염 및 항아토피 효과
Hyun Young Kim, Mi-Ja Lee, Woo Duck Seo, Sik-Won Choi, Sun Lim Kim1, Gun-Ho Jung1, and Hyeon Jung Kang*
Crop Foundation Division, National Institute of Crop Science, Rural Development Administration 1Department of Central Area Crop Science, National Institute of Crop Science, Rural Development Administration
농촌진흥청 국립식량과학원 작물기초기반과, 1농촌진흥청 국립식량과학원 중부작물부
This study evaluates the ability of corn silk (Zea mays L.) extract to function as a natural anti-inflammatory and anti-atopic therapeutic agent. The anti-inflammatory effects of corn silk were evaluated by measuring the inhibitory activities of nitric oxide (NO) and production of tumor necrosis factor-α (TNF-α). Anti-atopic effects were assessed by measuring the repression of thymus and activation-regulated chemokine (TARC). These results indicated that NICS-1 (corn silk ethanol extract) and NICS-3 (high maysin corn silk ethanol extract) functioned as anti-inflammatory agents by down-regulating LPS-induced NO and TNF-α. Additionally, two extracts showed weak repression of TARC expression levels in tumor necrosis factor TNF-α plus IFN-γ induced HaCaT cells, respectively. These results suggest that corn silk extracts have anti-inflammatory and anti-atopic activities, and thus have the potential to reduce and alleviate the symptoms associated with atopic dermatitis.
corn silk, anti-inflammatory, anti-atopic
한국식품과학회지 2017 Dec; 49(06): 710 - 713