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한국식품과학회지
→ 한국식품과학회지2021 ; 53(1): 46-54
Functional screening of Asparagus officinalis L. stem and root extracts
아스파라거스 줄기 및 뿌리 추출물의 기능성 검증
Joon-Hee Han1, Min Hong1, Jaehak Lee2, Da-Hye Choi1, Sun-Yeop Lee1, Tae-Hyung Kwon1, Jae-Hee Lee3, Yong-Jin Lee1, and Keun-Hyung Yu1,*
1Department of Research and Development, Chuncheon Bioindustry Foundation 2Department of Applied Animal Science, College of Animal Life Sciences, Kangwon National University 3Agro-food Research Institute, Gangwondo Agricultural Research and Extension Services (ARES)
한준희1 ·홍 민1 ·이재학2 ·최다혜1 ·이선엽1 ·권태형1 ·이재희3 ·이용진1 ·유근형1,*
1(재)춘천바이오산업진흥원 기술개발실, 2강원대학교 동물생명과학대학 동물식품응용학과, 3강원도농업기술원 농식품연구소
ABSTRACT
The biological activities of non-edible extracts of asparagus stems and roots were investigated using hot water and ethanol. The highest contents of rutin and total polyphenol were 31.74 mg/g and 20.14 mg GAE/g, respectively, in the stem hot water extract. ABTS and DPPH radical scavenging activities were 541.1±21.0 and 649.5±6.6 μg/mL, respectively, in stem hot water extract. All extracts were non-cytotoxic in HepG2 cells, but 200 μg/mL stem extracts tended to decrease the viability of RAW 264.7 cells. The highest xanthine oxidase inhibitory activity was 43.68% in the root hot water extract at 200 μg/mL. The expression level of MMP-9 was significantly decreased in the asparagus extracts. The highest GGT, AST, and LDH activities showed a concentration-dependent decrease in the stem ethanol extract. In conclusion, the presence of bioactive substances in the non-edible extracts of asparagus was confirmed for the development of extracts with antioxidant, hepatoprotective and anti-gout activities.
KEYWORD
anti-gout, antioxidant, asparagus, hepatoprotective, rutin
한국식품과학회지 2021 Feb; 53(1): 46 - 54
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